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Many clinicians favour macrogol for medication-related constipation because it’s gentle and doesn’t rely on you drinking large volumes. Stimulant laxatives are fine for an occasional night but aren’t meant for daily use over weeks without advice.Timing matters with some tablets. Wegovy (Semaglutide) tablets need to be taken on an empty stomach with only a small sip of water, followed by a wait before eating or taking anything else, so take fibre supplements and laxatives later in the day. Foundayo doesn’t carry the same strict food and water rules, which some patients find easier to fit around a bowel routine. Always check the leaflet that came with your medicine.If you need a laxative most days for more than a couple of weeks, speak to your prescriber rather than carrying on alone.

When to Seek Medical Advice

Most constipation on weight loss medication is a nuisance rather than a danger. Rarely, though, GLP-1 medicines have been linked to a blocked or paralysed bowel (ileus), and they can also raise the risk of gallstones and pancreatitis. These can start with symptoms that look like ordinary constipation, which is why some signs should never be waited out.

Call 999 or go to A&E if you have:

severe, constant tummy pain that’s getting worse
a swollen, hard abdomen with vomiting
no bowel movement and you can’t pass wind
severe pain in the upper tummy that spreads to your back

Contact your prescriber, GP or NHS 111 the same day if:

you haven’t opened your bowels for seven days or more, despite trying the steps above
laxatives haven’t helped after a few days
you notice blood in your stools, or stools that are black and tarry
you feel dizzy, very thirsty or are passing little dark urine, which can point to dehydration
you have pain under your right ribs, a high temperature or yellowing of the skin or eyes

Book a routine GP appointment if:

your bowel habits have changed for three weeks or more and it doesn’t seem to match your treatment
constipation keeps returning every time your dose goes up
you’re losing weight much faster than expected, or feel unwell in yourself

A lasting change in bowel habit can have causes unrelated to your medicine, including bowel cancer, so it’s worth getting checked rather than assuming the medication is to blame, particularly if you’re over 50.You can also report any side effect through the MHRA Yellow Card scheme. Newer medicines like Foundayo are under additional monitoring, so every report helps build the safety picture.

Should You Stop or Switch Your Medication?

Please don’t stop on your own. Constipation usually improves as your body adjusts, and stopping suddenly can bring hunger back quickly. A short conversation with your prescriber is the better route, because there are several middle-ground options.Your clinician might keep you on your current dose for an extra month instead of stepping up. They may drop you back a dose for a while, then try again once things have settled. Sometimes a regular laxative alongside treatment is all that’s needed. Occasionally, a different medicine suits someone better, and that’s a normal part of finding the right fit.People often ask how stimulant tablets compare with the newer injections on side effects. They’re quite different medicines with different profiles, and our article on Phentermine vs Mounjaro sets out the main differences in plain terms.Whatever you choose, remember that the medicine is only one part of the plan. Habits that ease constipation, such as more fibre, more water and daily walking, are the same ones that support long-term weight management once treatment ends. So the effort you put in now pays off twice.

Getting the Right Support

Constipation shouldn’t be the reason someone gives up on treatment that’s otherwise working for them. With a bit of planning, most people get on top of it within a few weeks, and the habits that fix it tend to make the whole weight loss journey feel easier.If you’re struggling, or you’d like a clinician to review your symptoms, our UK-based team is here to help. As an online Weight Loss Clinic, we can adjust your dose, talk you through remedies or look at whether a different medicine might suit you better. Get in touch, and don’t wait until it’s become a bigger problem.This article is for general information and isn’t a substitute for personal medical advice. Always read the patient leaflet that comes with your medicine and speak to a healthcare professional about any symptoms that worry you.

Achieve a stronger, more sculpted physique with Emsculpt Neo. This revolutionary treatment combines radiofrequency and high-intensity electromagnetic energy to simultaneously build muscle and reduce stubborn fat. Each 30-minute session delivers up to 20,000 supramaximal muscle contractions, helping strengthen, tone and define areas including the abdomen, buttocks, arms and thighs—all with no surgery or downtime.

2 session £398 (usually £700)

3 sessions £597 (usually £1050)

6 sessions £1194 (usually £2100)

8 sessions £1592 (usually £2800)

Target stubborn pockets of fat that resist diet and exercise with CoolSculpting Elite. Using advanced fat-freezing technology, this non-surgical treatment permanently eliminates fat cells to sculpt and contour your body. Enjoy natural-looking, long-lasting results with no surgery and minimal downtime.

4 Cycles £980 (usually £1,400)

6 Cycles £1470 (usually £2,100

8 Cycles £1960 (usually £3,160)

10 Cycles £2450 (usually £3,950)

The Ultimate skin-rejuvenation combination. Platinum Hydrafacial deeply cleanses, extracts and infuses the skin with intense hydration antiantioxidants, while SkinPen Microneedling stimulates natural collagen production to improve texture, tone and overall skin health. Together they deliver visible results and long-lasting glow.

Our exclusive combination packages pair Platinum HydraFacial with SkinPen Microneedling to maximise your skin results.

Package 1: 1 Platinum HydraFacial + 1 SkinPen Microneedling treatment.

Ultimate Transformation Package: 3 Platinum HydraFacials + 3 SkinPen Microneedling treatments.

1 session £299

3 sessions £799

Reduce the appearance of cellulite while improving skin firmness with Emtone. Combining radiofrequency and targeted mechanical energy, this advanced treatment stimulates collagen production to smooth uneven skin texture, tighten lax skin and restore a firmer, more youthful appearance.

Full legs 4 sessions £1,200 (usually £1,444)

Full legs 1 session £350 (usually £490)

Full legs + buttocks 4 sessions £1,800
(usually £2,394)

Full legs + buttocks 1 session £499

Morpheus8 Body combines advanced microneedling with radiofrequency energy to remodel the deeper layers of the skin. Designed to improve skin laxity, texture and contour, it stimulates collagen and elastin production, helping to tighten loose skin and improve the appearance of stretch marks, scars and uneven texture.

1 session £595 (usually £850)

3 sessions £1,725 (usually £2,350)

Reveal healthier, more radiant skin with HydraFacial. This multi-step treatment deeply cleanses, exfoliates, extracts impurities and infuses the skin with powerful hydrating serums and antioxidants. Suitable for all skin types, HydraFacial leaves your complexion instantly brighter, smoother and glowing with no downtime.

2 sessions £299 (usually £380)

Restore smoother, healthier-looking skin with SkinPen Microneedling. By creating precise micro-channels within the skin, this FDA-cleared treatment stimulates your body’s natural collagen and elastin production. It helps improve acne scars, fine lines, enlarged pores and uneven skin texture, revealing a fresher, more radiant complexion over time.