Regulated by the CQC & HIS

About us

Trusted Partnership with John Lewis

Read More About Our Partners

Founded in 2011 by Leading Plastic Surgeons

Our Heritage

Backed by 30+ NHS Consultants

Meet Our Aesthetic Doctors

Polynucleotides (Face & Under Eyes) Polynucleotides (Face & Under Eyes) Polynucleotides (Face & Under Eyes) Polynucleotides (Face & Under Eyes) Polynucleotides (Face & Under Eyes) Polynucleotides (Face & Under Eyes) Polynucleotides (Face & Under Eyes) Polynucleotides (Face & Under Eyes) Polynucleotides (Face & Under Eyes)

Polynucleotides (Face & Under Eyes)

From £450

Polynucleotides are an advanced regenerative treatment designed to repair, restore, and rejuvenate the skin from within, helping to fade pigmentation, evening skin tone and enhancing clarity for a natural and radiant glow. Using purified DNA (salmon DNA) fragments, Polynucleotides stimulate collagen production, boosting cell renewal, and supporting deep tissue repair, improving elasticity and hydration. This type of skin booster is gentle, biocompatible, and highly hydrating making it highly suitable for the delicate under-eye, reducing dark circles, smoothing fine lines, and restoring firmness without adding volume. Learn more

Choose the option that works best for you:

Treatment

Polynucleotides, also known as salmon DNA injections or skin boosters, have become one of the most sought-after regenerative treatments in aesthetics. Featured in Vogue, Tatler, Harper’s Bazaar, and The Times, this breakthrough therapy is praised for its ability to repair, hydrate, and rejuvenate the skin at a cellular level, delivering a natural, radiant glow. Loved by dermatologists, beauty editors, and celebrities including Jennifer Aniston, Kate Winslet, and Sienna Miller, Polynucleotides are celebrated as the next generation of skin boosters, revitalising tired skin, brightening under eyes, and restoring firmness and elasticity.

Choose the option that works best for you:

As Featured In

Founded in 2011 by NHS consultant doctors, Cavendish Clinic is a recognised and trusted brand and retail partner across the UK. We are also a trusted name in the press, regularly featured in leading publications for our expertise in advanced aesthetics, non-surgical treatments, and cosmetic surgery.  

BBC
Channel 4
GQ
ITV
John Lewis
Tatler
The Telegraph
Vanity Fair
Women’s Health
Men’s Health
BBC
Channel 4
GQ
ITV
John Lewis
Tatler
The Telegraph
Vanity Fair
Women’s Health
Men’s Health
BBC
Channel 4
GQ
ITV
John Lewis
Tatler
The Telegraph
Vanity Fair
Women’s Health
Men’s Health
BBC
Channel 4
GQ
ITV
John Lewis
Tatler
The Telegraph
Vanity Fair
Women’s Health
Men’s Health
BBC
Channel 4
GQ
ITV
John Lewis
Tatler
The Telegraph
Vanity Fair
Women’s Health
Men’s Health
BBC
Channel 4
GQ
ITV
John Lewis
Tatler
The Telegraph
Vanity Fair
Women’s Health
Men’s Health
BBC
Channel 4
GQ
ITV
John Lewis
Tatler
The Telegraph
Vanity Fair
Women’s Health
Men’s Health
BBC
Channel 4
GQ
ITV
John Lewis
Tatler
The Telegraph
Vanity Fair
Women’s Health
Men’s Health

Key Benefits

Stimulates collagen and elastin production: Encourages natural regeneration for firmer, smoother, and more resilient skin.

Deeply hydrates and restores skin quality: Improves elasticity, suppleness, and texture for a refreshed, youthful complexion.

Brightens and rejuvenates under eyes: Reduces dark circles, fine lines, and puffiness in the delicate under-eye area without adding volume.

Evens skin tone and fades pigmentation: Helps reduce the appearance of melasma, brown patches, and uneven tone for clearer, more luminous skin.

Repairs and renews at a cellular level: Supports long-term skin rejuvenation and radiance using advanced salmon DNA technology.

Choose the option that works best for you:

Key Benefits

Booking and Payment

This treatment is available as a single session or as part of a course for optimal results. We offer flexible payment options, including Klarna and Clearpay (pay in 3 installments). All bookings are valid for 12 months from the date of purchase.

How Many Sessions will I need?

For best results, a course of 3 treatments is usually recommended, with each session spaced 3-4 weeks apart. This allows the skin to gradually regenerate and strengthen from within, with results lasting for up to 6 months. In cases where under-eye darkness or skin concerns are milder, a shorter course of 2 treatments may be advised.

How long do the results last?

Visible improvements are seen within 2-3 weeks, with the skin becoming smoother, clearer, and more radiant.

In the under-eye area, polynucleotides can help to soften fine lines, refine texture, and restore a brighter, more refreshed appearance. With a full course of treatments, results can last for up to 6 months.

Procedure Time

Each treatment takes approximately 30-45 minutes, making it a quick and convenient option for natural skin rejuvenation.



Aftercare Advice

Mild swelling, redness, or small bumps may appear after treatment . This is a normal part of the healing process and should settle within a 24-48 hours. Avoid makeup, exercise, and heat exposure for the first 24 hours. To support recovery and maintain results, apply a gentle moisturiser and use SPF daily.

Disclaimer
All polynucleotide treatments require a doctor-led consultation to assess suitability. Results vary depending on individual skin condition, age, and lifestyle.

Get in Touch

Fill out the form below and our team will get back to you as soon as possible.

You may also like...

What our patients say

★ ★ ★ ★ ★

I visited the Cavendish Clinic for a Hydra Facial

10 January 2025

"I visited the Cavendish Clinic for a Hydra Facial the team were really professional and made me feel very relaxed and comfortable as soon as I arrived. The hydra facial was so deep and really cleaned my pores and super hydrated my face leaving me with a red carpet worthy glow. My skin also felt more plump and fine lines looked reduced. Would recommend this treatment."

MB

Maria Barnard

★ ★ ★ ★ ★

So I was called in for complimentary service

25 April 2025

"So I was called in for complimentary service after my first experience. This time I had my hydrafacial at Sloane Square and the staff and experienced was very pleasant. Aida did my hydrafacial treatment. She was very relaxing and friendly. I have to thank Martha from Fitrovia branch, who called me to arrange this and rectify my previous experience. I feel refreshed and look much glowy. Thank you"

SB

Sani Begum

★ ★ ★ ★ ★

I visited for Hydra facial recently

29 March 2025

"I visited for Hydra facial recently and I had an amazing experience with Cavendish Team. Fitzrovia Team is very Supportive and give me a good knowledge of skin. The facial was relexing and explained me step by step and I am so happy with my treatment. I look forward to seeing you again."

DP

Dipika Patel

★ ★ ★ ★ ★

Delighted with my skin consultation

23 April 2025

"Delighted with my skin consultation and first treatment. Eleni was wonderful."

C

CO