NEW Treatment Coming Soon: Polynucleotides

NEW Treatment Coming Soon: Polynucleotides

In the dynamic landscape of aesthetic advancements, a ground-breaking solution has emerged to redefine the standards of skin rejuvenation – Polynucleotide injectable treatments. Polynucleotides are the future of regenerative injectables. This treatment has now launched at Cavendish Clinic in Fitzrovia and here’s why we love it. It helps to enhance skin elasticity and firmness for the appearance of a more youthful and radiant complexion. But what exactly are polynucleotides, and what are the benefits of this treatment?


Polynucleotides, often abbreviated as PN or PDRN (Polydeoxyribonucleotide), are biological molecules consisting of long chains of nucleotide units. Nucleotides are the building blocks of DNA and RNA, and they consist of a sugar molecule, a phosphate group, and a nitrogenous base. In the context of medical and cosmetic applications, “polynucleotides” usually refers to a substance derived from salmon DNA or other sources. These polynucleotides are believed to have various therapeutic and regenerative properties. They are often used in treatments aimed at improving skin health, promoting wound healing, and stimulating tissue regeneration. Some potential applications include skin rejuvenation, hair loss treatment, and wound care. The idea behind using polynucleotides in these applications is that they may support cellular repair and regeneration processes, leading to improved tissue health and appearance.


This treatment is highly effective for reducing the appearance of dark circles under the eyes, reducing the appearance of fine lines and wrinkles, and improving skin texture, hair loss and skin rejuvenation.

Skin Rejuvenation: PNs stimulate the production of collagen, elastin, and other essential proteins, resulting in firmer, smoother, and more youthful-looking skin.

Reduced Fine Lines and Wrinkles: By promoting collagen synthesis, PNs effectively diminish the appearance of fine lines and wrinkles, restoring a more youthful complexion.

Improved Skin Texture: PNs enhance skin texture by boosting hydration, promoting cell turnover, and addressing imperfections such as scars and uneven pigmentation.

Reduces the appearance of dark eyes: PNs are especially effective in the eye area, as they stimulate higher hyaluronic acid synthesis, ensuring that the under-eye area remains hydrated and plump.

Hair Loss: Thanks to their bio-stimulatory properties, they can regenerate your hair follicles to stimulate hair growth after just a few treatments.


Ameela® is an innovative injectable solution based on natural polymerised polynucleotides. It is a highly moisturising gel that restores skin firmness and elasticity whilst protecting against cellular damage. Ameela offers three different products: Ameela® Eyes, Ameela® Face and Ameela® Rejuvenation.

Ameela® Eyes is specifically designed for the treatment of eyebags, and periocular wrinkles, and for enhancing the structural integrity of the skin, offering a more youthful and revitalised appearance. When applied to the periocular area, this polynucleotide gel initiates a bio-restructuration process, leading to the regeneration and bio-stimulation of the skin.

Ameela® Face is the leading choice in advanced skin rejuvenation. Specifically designed to address concerns of dehydrated skin, loss of elasticity, and the need for effective contouring, Ameela® Face stands out in the world of aesthetic treatments.

Ameela® Rejuvenation is designed to revitalise and restore your skin’s natural beauty. Utilising advanced polynucleotide technology, this treatment is your key to reducing wrinkles, improving skin tone, and rejuvenating the face, neck, hair, and hands.




Polynucleotide injections are typically administered in areas where skin rejuvenation is desired, including the face, neck, hands, and décolletage (chest). These injections aim to improve skin texture, reduce fine lines and wrinkles, and promote a more youthful appearance. The choice of specific areas depends on individual treatment goals, and consulting with a qualified healthcare professional is essential to tailor the procedure to individual needs.


You can typically observe initial improvements approximately 7-10 days after the initial treatment, and the full effects become evident within 3-4 weeks. It is at this point that we recommend scheduling your second and subsequent treatments to maintain and enhance the results. The effects can typically last up to 6 months before a maintenance session is required.


Our commitment to excellence and safety. At our clinic, all injectable procedures are performed by highly qualified and experienced doctors. This commitment to doctor-led injectables not only guarantees precision and artistry in every procedure but also prioritises your safety, well-being, and optimal outcomes.

Join our waitlist at our Fitzrovia Clinic today.


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